Videnskabelig referenceliste — 122 studier om Bioptron

Videnskabelig referenceliste — Bioptron Hyperlight Therapy

Herunder finder du den komplette liste over peer-reviewed videnskabelige publikationer og kliniske studier om Bioptron polariseret lysbehandling. Listen er organiseret efter behandlingsområde og indeholder 122 referencer fra internationale medicinske tidsskrifter.

Sårhealing og hudgenopretning

  1. Abd-Elhamed, T. G. et al. Polarized Light Therapy for Wounds: A Systematic Review. The Egyptian Journal of Hospital Medicine, 93, 7600-7609. (2022)
  2. Abd Al-kader, A. M. et al. Efficacy of polarized light in treatment of pressure ulcers. JMSCR, 3, 5800-5809. (2015)
  3. Abd El-Rashid NA et al. Effect of orange polarized light on Metacarpophalyngeal range of motion in pediatric hand burn. Bioscience Research, 16(3), 2417-22. (2019)
  4. Abd Elrashid, N. A. et al. Effect of orange polarized light on post burn pediatric scar. Journal of Physical Therapy Science, 30(10), 1227-1231. (2018)
  5. Abdel-Mageed, S. M. et al. Effect of Polarized Light as an Adjuvant Therapy on Wound Healing Process in Pediatrics. International Journal of Biophysics, 5(1), 18-23. (2015)
  6. Abdou WEB et al. Effect of Bioptron in Treating Cracked Nipples in Breast Feeding Women. World Journal of Medical Sciences, 16(1), 35-40. (2019)
  7. Ahmed, A. A. E. S. A. et al. Effect Of Polarized Light Therapy On Incisional Pain After Cesarean Section. European Journal of Molecular & Clinical Medicine, 7(10). (2020)
  8. Ali, M. E. et al. Efficacy of polarized light versus low intensity laser on healing of venous ulcers. South Valley University International Journal of Physical Therapy and Sciences, 3(1), 13-19. (2022)
  9. Allam MN et al. Polarized Light Therapy in the Treatment of Wounds: A Review. The International Journal of Lower Extremity Wounds. (2022)
  10. Aragona, S. E. et al. Photobiomodulation with polarized light in the treatment of cutaneous and mucosal ulcerative lesions. Journal of Biological Regulators and Homeostatic Agents, 31(2). (2017)
  11. Bahrami, H. et al. Low-Level Laser and Light Therapy After Total Knee Arthroplasty Improves Postoperative Pain and Functional Outcomes. Arthroplasty Today, 19, 101066. (2023)
  12. Bialozyt J. et al. Use of polarised lighting in support of treatment of pressure ulcers among patients after burns. Dermatologia Estetyczna, vol.20, 1 (114). (2018)
  13. Chen, B. et al. Distribution characteristics of pathogens in different stages of pressure ulcers and the therapeutic effect of linear polarized polychromatic light. Medicine, 102(42). (2023)
  14. Colic, M. M. et al. The use of polarized light in aesthetic surgery. Aesthetic Plastic Surgery, 28(5), 324-327. (2004)
  15. Durovic, A. et al. The effects of polarized light therapy in pressure ulcer healing. Vojnosanitetski Pregled, 65(12), 906-912. (2008)
  16. El Sayed, D. G. Hyperpolarized Light Therapy Versus Traditional Wound Care On Different Wound Types. NVEO Journal. (2021)
  17. El-Deen, H. B. et al. Polarized light versus light-emitting diode on healing of chronic diabetic foot ulcer. Romanian Journal of Biophysics, 24(2). (2014)
  18. Emam Mowafy, Z. M. et al. Wound Surface Area and Colony Count of Various Modes of Phototherapy. Egyptian Journal of Hospital Medicine, 85(2). (2021)
  19. Faraone, V. et al. Phototreatment of radiation-induced dermal injuries. Acta Medica Mediterranea, 24(2), 99-104. (2008)
  20. Feehan J et al. Therapeutic applications of polarized light: Tissue healing and immunomodulatory effects. Maturitas, 116, 11-17. (2018)
  21. Glogovac Kosanovic M et al. Effectiveness and safety of lysozyme chloride-based cream on healing of grade two pressure ulcers. Scripta Medica, 56(2), 245-53. (2025)
  22. INTSAR, S. W. et al. Effect of Negative Pressure Therapy versus Polarized Light Therapy on Chronic Wound Healing. The Medical Journal of Cairo University, 89, 655-660. (2021)
  23. Iordanou, P. et al. Effect of polarized light in the healing process of pressure ulcers. International Journal of Nursing Practice, 8(1), 49-55. (2002)
  24. Jankovic, A. Physical therapy of venous ulcers: effects of electroionotherapy and polarized light. Vascular Diseases, 4, 5. (2005)
  25. Jankovic, A. et al. Can you combine herbal therapy with physical agents in the treatment of venous leg ulcers? Complementary Medicine Research, 17(5), 266-269. (2010)
  26. Kymplova, J. et al. Contribution of phototherapy to the treatment of episiotomies. Journal of Clinical Laser Medicine & Surgery, 21(1), 35-39. (2003)
  27. Medenica, L. & Lens, M. The use of polarised polychromatic non-coherent light as a therapy for venous leg ulceration. Journal of Wound Care, 12(1), 37-40. (2003)
  28. Mohamed, E. A. E. et al. Effect of light therapy on episiotomy in postpartum women. International Journal of Therapies and Rehabilitation Research, 5(2), 9. (2016)
  29. Mohamed, M. H. et al. Interleukin-6 response to shock wave therapy versus polarized light therapy in treatment of chronic diabetic foot ulcers. Drug Invention Today, 11(11). (2019)
  30. Monstrey, S. J. et al. A conservative approach for deep dermal burn wounds using polarised-light therapy. British Journal of Plastic Surgery, 55(5), 420-426. (2002)
  31. Monstrey, S. et al. The effect of polarized light on wound healing. European Journal of Plastic Surgery, 24(8), 377-382. (2002)
  32. Mowafy, Z. M. E. et al. Low level laser therapy versus polarized light therapy on healing of foot burn. International Journal of Health Sciences, 6(S2), 13053-13063. (2022)
  33. Nardi GM et al. Phototherapy and Tailored Brushing Method in Patients with Facial and Dental Trauma. Healthcare, 9(5), 561. (2021)
  34. Nicolaou V et al. The Effectiveness of Polarized Light in Musculoskeletal, Skin Problems and Burns. AJBSR, 10(2). (2020)
  35. Rutteman B et al. Aeromonas wound infection in a healthy boy, and wound healing with polarized light. JMM Case Reports, 4(10). (2017)
  36. Simic, A. et al. Bioptron light therapy and thoracophrenolaparotomy wound healing in cardiac carcinoma patients. (2001)
  37. Stratman S et al. New Therapies for the Treatment of Diabetic Foot Ulcers. Surgical Technology International, 37, 37-47. (2020)
  38. Taha, M. M. et al. Effect of Polarized Light Therapy (Bioptron) on Wound Healing and Microbiota in Diabetic Foot Ulcer. Photobiomodulation, Photomedicine, and Laser Surgery. (2022)
  39. Zakaria Emam Mowafy. Pain and Fibrous Scarring Response to Polarized Light. International Journal of PharmTech Research, 9(5), 144-150. (2016)

Smertelindring og muskuloskeletale lidelser

  1. Abramovich, S. G. et al. The efficacy of the comprehensive use of naphthalan and non-selective chromotherapy in gonarthrosis. Drug Research, 70(04), 170-173. (2020)
  2. Bahrami, H. et al. Low-Level Laser and Light Therapy After Total Knee Arthroplasty. Arthroplasty Today, 19, 101066. (2023)
  3. Dimitrios S. Recommendations of Polarized Polychromatic Non-Coherent Light (Bioptron Light) in Management of Musculoskeletal Conditions. Annals of Physiotherapy & Occupational Therapy, 4(1). (2021)
  4. Dimitrios, S. The Effectiveness of Bioptron Light in Management of Acute Lateral Elbow Tendinopathy: A Case Report. (2019)
  5. Dimitrios, S. & Stasinopoulos, L. Treatment of carpal tunnel syndrome in pregnancy with Bioptron light. Laser Therapy, 26(4), 289-295. (2017)
  6. Huang, D. et al. Effects of Linear-Polarized Near-Infrared Light Irradiation on Chronic Pain. The Scientific World Journal, 2012, 567496. (2012)
  7. Mihaylova, M. et al. The effect of polarized polychromatic non-coherent light (Bioptron) therapy on patients with lower back pain. Scripta Scientifica Salutis Publicae, 3, 23. (2017)
  8. Mowafy, Z. M. E. et al. Polarized Light Therapy versus Pulsed Electromagnetic Field Therapy in Post-Herpetic Neuralgia of the Sciatic Nerve. European Chemical Bulletin, 12(4), 1094-1104. (2023)
  9. Nicolaou V et al. The Effectiveness of Polarized Light in Musculoskeletal, Skin Problems and Burns. AJBSR, 10(2). (2020)
  10. Petrovic, D. et al. Complex regional pain syndrome as a distal radius fracture complication. Annals of Physical and Rehabilitation Medicine, 61, e114. (2018)
  11. Raeissadat SA et al. The effect of polarized polychromatic noncoherent light (bioptron) therapy on patients with carpal tunnel syndrome. J Lasers Med Sci, 5(1), 39-46. (2014)
  12. Safaa MM et al. Effect of Bioptron Light Therapy on Pregnancy Related Carpal Tunnel Syndrome. The Medical Journal of Cairo University, 92(12), 1151-1156. (2024)
  13. Shiryan, G. T. et al. Effectiveness of polarized polychromatic light therapy on myofascial trigger points in chronic non-specific low back pain. Bulletin of Faculty of Physical Therapy, 27(1), 33. (2022)
  14. Skrypa, O. L. Evaluation of treatment effectiveness in temporomandibular joint dysfunction after mandibular fractures. Wiad Lek, 74(9), 2082-2086. (2021)
  15. Stasinopoulos, D. The use of polarized polychromatic non-coherent light as therapy for acute tennis elbow. Photomedicine and Laser Therapy, 23(1), 66-69. (2005)
  16. Stasinopoulos, D. et al. Comparison of effects of Cyriax physiotherapy, exercise and Bioptron light for lateral epicondylitis. Clinical Rehabilitation, 20(1), 12-23. (2006)
  17. Stasinopoulos, D. et al. The use of Bioptron light therapy for treatment of acute ankle sprains. Disability and Rehabilitation, 39(5), 450-457. (2017)
  18. Stasinopoulos, D. et al. Treatment of carpal tunnel syndrome with Bioptron light. Photomedicine and Laser Therapy, 23(2), 225-228. (2005)
  19. Stasinopoulos, D. et al. Comparing exercise program and low-level laser therapy with exercise and Bioptron light for lateral elbow tendinopathy. Photomedicine and Laser Surgery, 27(3), 513-520. (2009)
  20. Stasinopoulos D. et al. Bioptron Light in Patients with Chronic Rotator Cuff Tendinopathy. Journal of Physical Fitness, Treatment & Sports, 7(5). (2020)
  21. Stasinopoulos D. The Effectiveness of Bioptron Light in Chronic Patellar Tendinopathy. Journal of Clinical Cases & Reports. (2024)
  22. Taradaj, J. Evidence-Based Physiotherapy Level for Polarized Polychromatic Non-Coherent Light Applications. Physiotherapy Review, 25(1), 6-11.

Hudlidelser og dermatologi

  1. Begic-Rahic, J. & Vranic, S. The Application of Bioptron Light Therapy in Dermatology and Wound Healing. European Dermatology, 5. (2010)
  2. Choi M et al. In vivo and in vitro analysis of low level light therapy for sensitive skin. Lasers Med Sci, 28(6), 1573-9. (2013)
  3. El-Alfy, A. M. I. et al. Effect of Low-Level Laser Therapy Versus Bioptron on Psoriasis. Journal of Advanced Zoology, 44(S3), 39-49. (2023)
  4. Hass HL. Therapeutic effects of BIOPTRON light in cosmetic medicine — Acne vulgaris. Krankenpfl J, 36(10), 394-395. (1998)
  5. Kolenko. Light therapy in complex treatment of patients with herpes zoster. National Medical University, Kiev. (2017)
  6. Leguina-Ruzzi, A. et al. Treatment of non-atopic dermatitis with polarized UV-free polychromatic light: A case report. Clinics and Practice, 9(3), 1161. (2019)
  7. Mahran, H. G. et al. Low Level Laser Versus Polarized Light in the Treatment of Acne Vulgaris. Egyptian Journal of Physical Therapy and Rehabilitation. (2025)
  8. Mohamed, M. H. et al. Ultrasonographic Response to Polarized Light Therapy in the Treatment of Atopic Dermatitis. Egyptian Journal of Physical Therapy, 9(1), 21-28. (2022)
  9. Nosseir, A. A. et al. Polarized Light Therapy versus Betamethasone Phonophoresis in Treatment of Psoriasis. Saudi Journal of Medicine & Pharmaceutical Sciences, 6(1), 143-148. (2020)
  10. Samuel Abdelmaseih Ibrahim Zaki et al. Effect of polarized light therapy on acne vulgaris in women with polycystic ovarian syndrome. International Journal of Recent Advances in Multidisciplinary Research, 11(04), 9725-9732. (2024)
  11. Taha, M. M. et al. Effect of Bioptron on Wound Healing and Microbiota in Diabetic Foot Ulcer. Photobiomodulation, Photomedicine, and Laser Surgery. (2022)
  12. Waked, I. S. & Abdelhamid, N. D. The efficacy of bioptron light in the treatment of plaque psoriasis. World Journal of Pharmaceutical Research, 4(5), 366-376. (2015)
  13. Zakaria Mowafy et al. Polarized Light Therapy Versus Pulsed Electromagnetic Field Therapy on Chronic Rhinosinusitis. IJPRIF, 9(4), 41-47. (2016)

Tandpleje og oral medicin

  1. Nardi, G. M. et al. Use of photobiomodulation induced by polarized polychromatic non-coherent light in adult chronic periodontitis. Journal of Biological Regulators and Homeostatic Agents, 33(1), 293-297. (2019)
  2. Nardi, G. M. et al. Treatment of Peri-Implant Mucositis with Standard of Care and Bioptron Hyperlight Therapy: A Randomized Clinical Trial. International Journal of Environmental Research and Public Health, 19(9), 5682. (2022)
  3. Nemeth, L. et al. The impact of photobiomodulation of major salivary glands on caries risk. Lasers in Medical Science, 35(1), 193-203. (2020)
  4. Petruzzi, M. et al. Polarized Polychromatic Noncoherent Light (Bioptron) as Adjunctive Treatment in Chronic Oral Mucosal Pain. Photobiomodulation, Photomedicine, and Laser Surgery, 37(4), 227-232. (2019)

Pædiatri og børn

  1. Abd El-Rashid NA et al. Effect of orange polarized light on pediatric hand burn range of motion. Bioscience Research, 16(3), 2417-22. (2019)
  2. Abd Elrashid, N. A. et al. Effect of orange polarized light on post burn pediatric scar. Journal of Physical Therapy Science, 30(10), 1227-1231. (2018)
  3. Abdel-Mageed, S. M. et al. Effect of Polarized Light as Adjuvant Therapy on Wound Healing in Pediatrics. International Journal of Biophysics, 5(1), 18-23. (2015)
  4. Falus A et al. Genome-wide gene expression study: anti-inflammatory effect of polarized light in recurrent childhood respiratory disease. Inflammation Research, 60(10), 965-972. (2011)
  5. Khan MA, Erdes SI. Polychromatic Polarized Light in Prophylaxis and Treatment of Respiratory System Diseases in Children and Adolescents. Pediatrician's Practice Moscow. (2009)
  6. Khan MA, Erdes SI. The Application of BIOPTRON Polychromatic Incoherent Polarized Light in Allergic Diseases in Children. Pediatrician's Practice Moscow. (2010)
  7. Rutteman B et al. Aeromonas wound infection and wound healing with polarized light. JMM Case Reports, 4(10). (2017)

Sæsonbetinget affektiv lidelse (SAD) og depression

  1. Avery DA et al. Bright light therapy of subsyndromal seasonal affective disorders in the workplace. Acta Psychiatrica Scandinavica, 103, 267-274. (2001)
  2. Eastman CI et al. Bright light treatment of winter depression: a placebo-controlled trial. Archives of General Psychiatry, 55, 883-889. (1998)
  3. Golden, R. N. et al. The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis. American Journal of Psychiatry, 162(4), 656-662. (2005)
  4. Kasper, S. et al. Phototherapy in individuals with and without subsyndromal seasonal affective disorder. Archives of General Psychiatry, 46(9), 837-844. (1989)
  5. Kosanovic Rajacic, B. et al. Plasma Brain-Derived Neurotrophic Factor Levels before and after Bright Light Therapy in Treatment-Resistant Depression. Biomolecules, 13, 1425. (2023)
  6. Kosanovic Rajacic, B. et al. Increased Interleukin-6 Levels in Responders with Treatment-Resistant Depression After Bright Light Therapy. Biomolecules, 15(2), 295. (2025)
  7. Lee TM, Chan CC. Dose-response relationship of phototherapy for seasonal affective disorder: a meta-analysis. Acta Psychiatrica Scandinavica, 99, 315-323. (1999)
  8. Lewy, A. J. et al. Morning vs evening light treatment of patients with winter depression. Archives of General Psychiatry, 55(10), 890-896. (1998)
  9. Lieverse, R. et al. Bright light in elderly subjects with nonseasonal major depressive disorder: a double blind randomised clinical trial. Trials, 9. (2008)
  10. Partonen, T. & Lonnqvist, J. Bright light improves vitality and alleviates distress in healthy people. Journal of Affective Disorders, 57(1-3), 55-61. (2000)
  11. Sit DK et al. Adjunctive bright light therapy for bipolar depression: a randomized double-blind placebo-controlled trial. American Journal of Psychiatry, 175, 131-139. (2018)
  12. Swedo, S. E. et al. A controlled trial of light therapy for the treatment of pediatric seasonal affective disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 36(6), 816-821. (1997)
  13. Terman, M. et al. A controlled trial of timed bright light and negative air ionization for treatment of winter depression. Archives of General Psychiatry, 55(10), 875-882. (1998)
  14. Tsai, Y. F. et al. The effects of light therapy on depressed elders. International Journal of Geriatric Psychiatry, 19(6), 545-548. (2004)

Cellulære mekanismer og grundforskning

  1. Bogacheva ON et al. Enhancement of fibroblast growth promoting activity of human blood after irradiation with visible and infrared polarized light. Tsitologiia, 46(2), 159-171. (2004)
  2. Bolton P et al. The Effect of Polarized Light on the Release of Growth Factors from the U-937 Macrophage-Like Cell Line. Laser Therapy, 2(3), 33-37. (1992)
  3. Cicek, G. et al. Use of quantum hyperlight technology in photobiomodulation on stem cells: an in vitro study. Lasers in Medical Science, 40(1). (2025)
  4. Falus A et al. Genome-wide gene expression: anti-inflammatory effect of polarized light in recurrent childhood respiratory disease. Inflammation Research, 60(10), 965-972. (2011)
  5. Feehan J et al. Therapeutic applications of polarized light: tissue healing and immunomodulatory effects. Maturitas, 116, 11-17. (2018)
  6. Fenyo M. Theoretical and experimental basis of biostimulation by laser irradiation. Optics and Laser Technology, August, 209-215. (1984)
  7. Fenyo M et al. Opposite effect of linearly polarized light on biosynthesis of interleukin-6 in a human B lymphoid cell line and peripheral monocytes. Cell Biology International, 26(3), 265-269. (2002)
  8. Karu TI. Molecular Mechanism of the Therapeutic Effect of Low-Intensity Laser Radiation. Lasers in the Life Sciences, 2(1), 53-74. (1988)
  9. Karu T. Primary and secondary mechanisms of action of visible to near-IR radiation on cells. Journal of Photochemistry and Photobiology B, 49, 1-17. (1999)
  10. Kubasova T et al. Investigations on biological effect of polarized light. Photochemistry and Photobiology, 48(4), 505-509. (1988)
  11. Kubasova T et al. Effect of visible light on some cellular and immune parameters. Immunology and Cell Biology, 73, 239-244. (1995)
  12. Lim JH et al. The effects of daily irradiation with polychromatic visible polarized light on human lymphocyte populations. Photomed Laser Surg, 26(4), 361-6. (2008)
  13. Lubart R et al. Photobiostimulation as a Function of Different Wavelengths. Laser Therapy, 12, 38-41.
  14. Mester, E. et al. The biomedical effects of laser application. Lasers in Surgery and Medicine, 5(1), 31-39. (1985)
  15. Roberts JE. Visible light induced changes in the immune response through an eye-brain mechanism. Journal of Photochemistry and Photobiology B, 29, 3-15. (1995)
  16. Roberts JE. Update on the Positive Effects of Light in Humans. Photochemistry and Photobiology, 81, 490-492. (2005)
  17. Samoilova KA et al. Enhancement of blood growth promoting activity after exposure to visible and infrared polarized light. Photochemistry and Photobiology Sciences, 3, 96-101. (2004)
  18. Samoilova KA et al. Improvement of microcirculation in diabetic patients after irradiation with visible and combined visible and near infrared light. Minimax Journal. (2006)
  19. Samoilova KA et al. Role of Nitric Oxide in Visible Light-Induced Rapid Increase of Skin Microcirculation — Diabetic Patients. Photomedicine and Laser Surgery, 26(5), 433-442. (2008)
  20. Samoilova KA et al. Role of Nitric Oxide in Visible Light-Induced Rapid Increase of Skin Microcirculation — Healthy Volunteers. Photomedicine and Laser Surgery, 26(5), 443-449. (2008)
  21. Simunovic Z et al. Wound Healing Using Low-Level Laser Therapy Treatment: A Randomized Clinical Study of 74 Patients. Journal of Clinical Laser Medicine & Surgery, 18(2), 67-73. (2000)
  22. Young S et al. Macrophage Responsiveness to Light Therapy. Lasers in Surgery and Medicine, 9, 497-505. (1989)
  23. Zhevago NA et al. Polychromatic light stimulates DNA synthesis in human peripheral blood lymphocytes in vivo and in vitro. Photochemistry and Photobiology, 82(5), 1301-1308. (2006)
  24. Zhevago NA & Samoilova KA. Pro- and Anti-inflammatory Cytokine Content after Transcutaneous Irradiation with Polychromatic Visible and Infrared Light. Photomedicine and Laser Surgery, 24(2), 129-139. (2006)
  25. Zhevago NA et al. Changes in the expression of membrane markers and number of human blood monocytes after courses of visible and infrared light. Tsitologiia, 45(2), 179-19. (2003)
  26. Zhevago NA et al. Polychromatic light in post-surgical immunorehabilitation of breast cancer patients. Journal of Photochemistry and Photobiology B, 166, 44-51. (2017)
  27. Zimin A et al. Proliferation of normal and tumor cells at the presence of serum from breast cancer patients after phototherapy. Tsitologiia, 52(9), 785-792. (2010)

Denne referenceliste indeholder 122 videnskabelige publikationer om Bioptron Hyperlight Therapy organiseret efter behandlingsområde. Studierne er publiceret i internationale peer-reviewed tidsskrifter og dækker perioden 1984–2025.

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